Clinical Trials Directory

Trials / Completed

CompletedNCT02413593

Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination Tablet With Ribavirin for 12 Weeks in Treatment-naive Adults With Chronic HCV Genotype 3 Infection

A Phase 2 Open- Label Study to Evaluate The Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination Tablet With Ribavirin for 12 Weeks in Treatment-naïve Patients With Chronic HCV Genotype 3 Infection

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
111 (actual)
Sponsor
Gilead Sciences · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study will evaluate the antiviral efficacy, safety, and tolerability of ledipasvir/sofosbuvir (LDV/SOF) fixed dose combination (FDC) plus ribavirin (RBV) in treatment-naive adults with chronic genotype 3 hepatitis C virus (HCV) infection.

Conditions

Interventions

TypeNameDescription
DRUGLDV/SOF90/400 mg FDC tablet administered orally once daily
DRUGRBVTablets administered orally in a divided daily dose according to package insert weight-based dosing recommendations (\< 75 kg = 1000 mg and ≥ 75 kg = 1200 mg)

Timeline

Start date
2015-04-01
Primary completion
2015-12-01
Completion
2016-01-01
First posted
2015-04-10
Last updated
2018-11-16
Results posted
2017-02-14

Locations

15 sites across 1 country: Canada

Source: ClinicalTrials.gov record NCT02413593. Inclusion in this directory is not an endorsement.