Trials / Completed
CompletedNCT02412579
Genetic Profiling of Liver Cancer in Patients Undergoing Liver Transplantation
Circulating MicroRNA Isoforms as Biomarkers in Hepatocellular Carcinoma and Associated Liver Transplantation
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (actual)
- Sponsor
- Baylor Research Institute · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine whether genetic markers unique to liver cancer are present and to assess usefulness as a diagnostic tool.
Detailed description
Hepatocellular carcinoma (HCC) is the most common form of liver cancer and a growing trend worldwide. Decision-making regarding treatment for patients is limited by the lack of clinically actionable biomarkers. This is pronounced in the case for determining and monitoring liver transplant recipients. In an effort to improve diagnosis, the use of circulating serum-based microRNA isoforms (isomiRs) can serve as non-invasive, screening biomarkers in HCC patients pre- and post-transplantation of the liver.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | None - Standard of Care |
Timeline
- Start date
- 2015-03-01
- Primary completion
- 2022-03-17
- Completion
- 2022-03-17
- First posted
- 2015-04-09
- Last updated
- 2022-07-20
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02412579. Inclusion in this directory is not an endorsement.