NCT02410980

Assessing the Effects of Tretinoin Cream on Human Skin With Optical Imaging Technologies

In-vivo Non-invasive Skin Imaging Pilot Study to Assess the Effects of Tretinoin Cream Using Multi-photon Microscopy and Multi-spectral Imaging

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: University of California, Irvine · Academic / Other
• Sex: Female
• Age: 45 Years
• Healthy volunteers: Accepted

Summary

The researchers will assess the effects of treatment with tretinoin cream on human skin by using non-invasive optical imaging technologies.

Detailed description

The researchers will evaluate changes in the dermis and skin properties as the effect of treatment with Tretinoin cream (0.1%) by using the following optical imaging techniques. 1. Multiphoton microscopy using a clinical tomograph (MPTflex, Jenlab, Germany) 2. Multispectral Imaging using a device developed at Beckman Laser Institute, UC Irvine

Conditions

• Collagen Fibril Alteration

Interventions

Type	Name	Description
DRUG	Tretinoin cream 0.1%	Assessment of the skin change

Timeline

• Start date: 2015-08-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2015-04-08
• Last updated: 2022-11-01

Locations

1 site across 1 country: United States