NCT02408289

The Randomized Controlled Cocoa-Appetite Trial

A Pilot Randomized Human Trial on The Effects of Cocoa on Appetite.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Brooklyn College of the City University of New York · Academic / Other
• Sex: Male
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine whether high-flavonoid cocoa can decrease appetite in humans. In addition the study is designed to test epicatechin, a compound found in cocoa and procyanidins, a class of compounds found in cocoa, for their ability to decrease appetite in humans.

Detailed description

The study is a four-way randomized double-blinded crossover trial with randomization balanced for beverage and lab visit order.

Conditions

• Obesity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Lo-Flav	low-flavonoid cocoa powder with 0 mg of procyanidins and 0 mg epicatechin per kg of body weight will be consumed as a beverage.
DIETARY_SUPPLEMENT	Hi-Flav	High-flavonoid cocoa powder with 3.8 mg procyanidins per kg of body weight and 0.6 mg Epicatechin per kg of body weight will be consumed as a beverage.
DIETARY_SUPPLEMENT	Epicatechin	Low-flavonoid cocoa powder plus 1 mg epicatechin per kg of body weight will be consumed as a beverage
DIETARY_SUPPLEMENT	Procyanidins	Low-flavonoid cocoa powder plus 3.7 mg procyanidins per kg of body weight will be consumed as a beverage.

Timeline

• Start date: 2015-03-01
• Primary completion: 2015-05-01
• Completion: 2015-05-01
• First posted: 2015-04-03
• Last updated: 2016-01-13

Locations

1 site across 1 country: United States