NCT02407652

Cognitive Control Training for Remitted Depressed Patients

Cognitive Control Training as a Preventive Intervention for Depression: A Double-blind Randomized Controlled Trial Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 68 (actual)
• Sponsor: University Ghent · Academic / Other
• Sex: All
• Age: 23 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to explore the effectiveness of an internet-delivered cognitive control training as a preventive intervention for remitted depressed patients.

Detailed description

Prospective studies have linked impaired cognitive control to increased cognitive vulnerability for future depression. Importantly, experimental studies indicate that cognitive control training can be used to reduce rumination and depressive symptomatology in MDD samples. Furthermore, studies exploring the potential of cognitive control training in at-risk undergraduate students indicate that cognitive control training has beneficial effects on rumination, an important vulnerability factor for depression. Provided that remitted depressed patients form a high-risk group for developing future depressive episodes, the current study will explore whether internet-delivered cognitive control training can be used to reduce vulnerability for future depression in remitted depressed patients. The investigators will explore effects on depressive symptomatology, (mal-)adaptive emotion regulation (directly following training and at 3 months follow-up), and indices of functioning (at 3 months follow-up).

Conditions

• Major Depression in Remission

Interventions

Type	Name	Description
BEHAVIORAL	Cognitive Control Training	10 adaptive Paced Auditory Serial Addition Task (PASAT) sessions, 400 trials each
BEHAVIORAL	Low Cognitive Load Training	10 low cognitive load sessions, 400 trials each

Timeline

• Start date: 2014-12-01
• Primary completion: 2015-10-01
• Completion: 2015-10-01
• First posted: 2015-04-03
• Last updated: 2015-12-17

Locations

1 site across 1 country: Belgium