NCT02407548

The Effects of Dietary Supplement of Coenzyme Q10（CoQ10） on Dyslipidemia

The Effects of Dietary Supplement of Coenzyme Q10 on Dyslipidemia

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

In previous study the investigators found that CoQ10 can improve cholesterol efflux from macrophages in cell model, ApoE mice model and small-scale of healthy volunteers. In addition, CoQ10 has strong antioxidant activity and is an essential factor of mitochondria electron transport chain. So the investigators hypothesize that CoQ10 may have some health promotion effect on dyslipidemia, risk factor of atherosclerosis and other cardiovascular diseases. On this purpose, the investigators are going to recruit 150 dyslipidemia patients to supply CoQ10+vitamin E or CoQ10 alone or placebo in different doses for 24 weeks to explore the effects of CoQ10 on cholesterol efflux and lipid profiles on dyslipidemia.

Conditions

• Dyslipidemia

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	coenzyme Q10 vitamin E softgel	4 coenzyme Q10 and vitamin E softgels per day for 24 weeks. Keep normal lift style unchanged.
DIETARY_SUPPLEMENT	coenzyme Q10 softgel	4 coenzyme Q10 softgels per day for 24 weeks. Keep normal lift style unchanged.
DIETARY_SUPPLEMENT	placebo softgel	4 placebo softgels per day. Keep normal lift style unchanged.

Timeline

• Start date: 2015-07-01
• Primary completion: 2017-04-01
• Completion: 2017-04-01
• First posted: 2015-04-03
• Last updated: 2017-06-22

Locations

1 site across 1 country: China