NCT02400671

Mobile Strategies for Women's and Children's Health: Optimizing Adherence and Efficacy of PMTCT/ART

Evaluation of Mhealth Strategies to Optimize Adherence and Efficacy of PMTCT/ART

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 825 (actual)
• Sponsor: University of Washington · Academic / Other
• Sex: Female
• Age: 14 Years
• Healthy volunteers: Accepted

Summary

The investigators are conducting a 3-arm randomized trial comparing the effects of unidirectional SMS (ie: "push" messaging to participant) vs. bidirectional SMS dialogue between participant and provider vs. control (no SMS) among HIV-infected Kenyan mothers in Kenyan PMTCT-ART for outcomes of ART adherence and retention in care.

Detailed description

The investigators will compare trial arms for impact on maternal retention, adherence, virologic failure and resistance and infant HIV or HIV-free survival. The investigators will determine correlates of maternal loss to follow-up and virologic failure and correlates of infant HIV in the overall study and stratified by trial arm. In the bidirectional SMS arm, the investigators will determine the rate of SMS interactivity, impact of critical time-points on messaging, and characteristics of high and low 'interactors'. The investigators will determine cost-effectiveness of unidirectional and bidirectional SMS interventions. These data will contribute a potential scale-able strategy to improve PMTCT-ART as programs aspire to 'virtual elimination' of infant HIV.

Conditions

• mHealth
• PMTCT
• Adherence, Medication
• SMS
• Maternal Health
• HIV/AIDS

Interventions

Type	Name	Description
BEHAVIORAL	SMS messaging

Timeline

• Start date: 2015-11-01
• Primary completion: 2020-01-31
• Completion: 2020-02-28
• First posted: 2015-03-27
• Last updated: 2022-11-02
• Results posted: 2022-11-02

Locations

6 sites across 1 country: Kenya