NCT02398084

Particle Sizing of Masticated Tree Nuts - Cashews and Walnuts

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: King's College London · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The investigators want to understand how oral processing (chewing) of nuts affects particle size and the presence of lipid (fat) on the cut surfaces. The main objective of the study is to: Measure the size of nut particles that have been chewed sufficiently to be swallowed. The secondary objective of this study is to: Measure any changes in lipid content due to chewing and compare it to a prediction from a theoretical model. The investigators have developed a theoretical model for determining the release of nutrients from plant foods, specifically lipid (fat) from almonds. The model has been used to calculate the amount of lipid released from chewed almonds. The model shows that only about 10% of the lipid is immediately released. The investigators require information on the particle size distribution (number of particles of each size) for other chewed nuts to calculate the amount of lipid released for other nuts. This will allow us to check the validity of our model for other foods.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Chewing of nuts	The volunteers will be asked to chew and spit 8 portions (4-5 g) of nuts (cashews or walnuts) on two separate visits. They will provide samples for particle sizing. Two portions will be used as practice samples in order to measure the number of chews. Two portions will be sieved. Two portions will be measured by laser diffraction. Two portions will be frozen for later lipid analysis.

Timeline

• Start date: 2015-02-01
• Primary completion: 2015-04-01
• Completion: 2016-04-01
• First posted: 2015-03-25
• Last updated: 2016-03-09

Locations

1 site across 1 country: United Kingdom