NCT02397577

Reference Values for Gastric Emptying

Normal Values for Gastric Emptying in a 13C-octanoate Breath Test Using a Solid Test Meal

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 75 (estimated)
• Sponsor: University of Zurich · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Healthy volunteers will ingest a 13C-octaoate containing test meal and 13C in expiratory air will be followed. Normal values will be calculated data of these tests.

Detailed description

This is a clinical study for establishing reference values in a 13C-octanoate breath test and a 13C-sodium acetate breath test. Healthy volunteers (n=75) will eat a solid test meal of scrambled eggs and toast containing 13C-octanoate. 13C-content of exhaled air will be measured at baseline and followed for the next 4 hours. One week later, the healthy volunteers (n=75) will drink a standardized nutritional shake (Ensure Plus Vanille, Abbott) containing 13C-sodium acetate. 13C-content of exhaled air will be measured at baseline and for the next 4 hours. Estimated gastric emptying time will be calculated using established algorithms.

Conditions

• Delayed Gastric Emptying

Interventions

Type	Name	Description
OTHER	Solid test meal, liquid test meal on two separate occations	13C labeld solid test meal, 13C labeld liquid test meal on two separate occations

Timeline

• Start date: 2015-02-01
• Primary completion: 2018-05-01
• Completion: 2018-05-01
• First posted: 2015-03-25
• Last updated: 2018-07-05

Locations

1 site across 1 country: Switzerland