NCT02396901

Goal Direct Therapy to Prevent Acute Kidney Injury

Goal Direct Therapy to Prevent Acute Kidney Injury After Cardiac Surgery

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 214 (estimated)
• Sponsor: University of Sao Paulo · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is an randomised controlled trial to investigate an strategy based in a protocol in prevention of acute kidney injury after cardiac surgery.

Detailed description

This is a prospective, randomized controlled trial to assess the influence of use of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) in the development of the Acute Kidney Injury in the postoperative period of cardiac surgery. Patients undergoing cardiac surgery at the Heart Institute (InCor) - Brazil, will be randomized and in accordance with a list of random numbers, generated by a computer program, will be allocated in one of the groups (GDT or standard).

Conditions

• Acute Kidney Injury

Interventions

Type	Name	Description
OTHER	Goal Direct Therapy	Goal Direct Therapy - in this group patients will receive the standard treatment according with institutional protocol.

Timeline

• Start date: 2015-04-01
• Primary completion: 2015-12-01
• Completion: 2017-04-01
• First posted: 2015-03-24
• Last updated: 2015-03-24