Clinical Trials Directory

Trials / Completed

CompletedNCT02396342

Trial of AAV5-hFIX in Severe or Moderately Severe Hemophilia B

A Phase I/II, Open-label, Uncontrolled, Single-dose, Dose-ascending, Multi-centre Trial Investigating an Adeno-associated Viral Vector Containing a Codon-optimized Human Factor IX Gene (AAV5-hFIX) Administered to Adult Patients With Severe or Moderately Severe Hemophilia B

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
10 (actual)
Sponsor
CSL Behring · Industry
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study evaluates how safe gene therapy treatment with AAV5-hFIX is in adult patients with severe or moderately severe hemophilia B and severe bleeding type.

Conditions

Interventions

TypeNameDescription
GENETICAAV5-hFIXAAV5hFIX gene therapy

Timeline

Start date
2015-06-10
Primary completion
2021-04-15
Completion
2021-04-15
First posted
2015-03-24
Last updated
2022-06-27
Results posted
2022-06-27

Locations

7 sites across 3 countries: Denmark, Germany, Netherlands

Source: ClinicalTrials.gov record NCT02396342. Inclusion in this directory is not an endorsement.