NCT02395458

Efficacy on Helicobacter Pylori Eradication With Two Antibiotic Regimens

Efficacy on Helicobacter Pylori Eradication With Sequential Antibiotic Compared to Triple Therapy for 14 Days

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 142 (actual)
• Sponsor: Coordinación de Investigación en Salud, Mexico · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Clinical trial to compare efficacy on eradicating Helicobacter pylori with two antibiotic strategies: sequential with amoxicillin and omeprazole 5 days and clarithromycin with metronidazole and omeprazole 5 days or omeprazole with clarithromycin and amoxicillin 14 days.

Detailed description

In patients with documented infection with Helicobacter pylori after endoscopy and biopsy, two modalities of treatment were compared, and after a control endoscopy and biopsy, eradication was assessed as well as side effects of both treatments.

Conditions

• Helicobacter Infections

Interventions

Type	Name	Description
DRUG	Sequential therapy	Patient receive Omeprazole plus amoxicillin during 5 days and then omeprazole plus clarithromycin and metronidazole during another 5 days
DRUG	Triple therapy	Patient receive Omeprazole plus amoxicillin and Clarithromycin during 14 days

Timeline

• Start date: 2013-03-01
• Primary completion: 2015-02-01
• Completion: 2015-02-01
• First posted: 2015-03-23
• Last updated: 2015-03-23