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Trials / Completed

CompletedNCT02395133

A Study to Confirm the Efficacy and Safety of Different Dupilumab Dose Regimens in Adults With Atopic Dermatitis (AD)

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Investigating the Efficacy and Safety of Multiple Dupilumab Dose Regimens Administered as Monotherapy for Maintaining Treatment Response in Patients With Atopic Dermatitis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
422 (actual)
Sponsor
Regeneron Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary objective of the study was to assess the ability of different Dupilumab dose regimens, administered as monotherapy, to maintain the treatment response achieved after 16 weeks of initial treatment with Dupilumab monotherapy compared to placebo.

Conditions

Interventions

TypeNameDescription
DRUGDupilumabSubcutaneous injection of Dupilumab 300 mg alternatively with placebo (matched to Dupilumab) was administered.
DRUGPlaceboSubcutaneous injection of Placebo (for Dupilumab) was administered once weekly (QW).

Timeline

Start date
2015-03-25
Primary completion
2016-07-01
Completion
2016-10-18
First posted
2015-03-20
Last updated
2020-03-11
Results posted
2018-10-17

Source: ClinicalTrials.gov record NCT02395133. Inclusion in this directory is not an endorsement.

A Study to Confirm the Efficacy and Safety of Different Dupilumab Dose Regimens in Adults With Atopic Dermatitis (AD) (NCT02395133) · Clinical Trials Directory