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Active Not RecruitingNCT02393625

Study of Safety and Efficacy of Ceritinib in Combination With Nivolumab in Patients With ALK-positive Non-small Cell Lung Cancer

A Multi-center, Open-label Study to Assess the Safety and Efficacy of Combination Ceritinib (LDK378) and Nivolumab in Adult Patients With Anaplastic Lymphoma Kinase (ALK)-Positive Non-small Cell Lung Cancer (NSCLC)

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
57 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
18 Years – 100 Years
Healthy volunteers
Not accepted

Summary

This is an open label multi center trial to determine the safety and efficacy of ceritinib in combination with nivolumab in ALK-positive NSCLC patients

Conditions

Interventions

TypeNameDescription
DRUGCeritinib (LDK378)
DRUGNivolumab

Timeline

Start date
2015-05-27
Primary completion
2027-04-09
Completion
2027-04-09
First posted
2015-03-19
Last updated
2026-04-02

Locations

12 sites across 8 countries: United States, Australia, Belgium, Canada, Hong Kong, Italy, Singapore, Spain

Regulatory

Source: ClinicalTrials.gov record NCT02393625. Inclusion in this directory is not an endorsement.

Study of Safety and Efficacy of Ceritinib in Combination With Nivolumab in Patients With ALK-positive Non-small Cell Lun (NCT02393625) · Clinical Trials Directory