NCT02393287

Retroprospective Real Life Observatory of Eribulin

Activity and Toxicity Profile of Eribulin Mesylate in Pretreated Metastatic Breast Cancer: an Observational Multicentric Retroprospective Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 753 (actual)
• Sponsor: Institut Cancerologie de l'Ouest · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objective of this observatory is to evaluate the effecacy of Eribulin in patients with metastatic breast cancer on a recent prescription period. Part of the data collection will be retrospective and the other part will be prospective for patients started treatment by Eribulin between November 2014 and September 2015. It will allow a better assessment on the safety profile of this drug.

Detailed description

Approximately one third of patients treated for localized breast cancer will present a metastatic evolution and 5% of patients are metastatic immediately. At this stage, the malignancy is incurable with a median survival from 2 to 3 years. Metastatic breast cancer treatment is part of a multidisciplinary approach. These two objectives are to prolong survival and improve quality of life. At present, there is no standard after the first line of chemotherapy, with fe strategy studies Eribulin is now a new therapeutic option to consider. Many patients have benefited from this treatment option and it seems interesting to evaluate in real life the effecacy and tolerance of chemotherapy.

Conditions

• Metastatic Breast Cancer

Interventions

Type	Name	Description
OTHER	Eribulin (ReProLine)	this is an observational trial ; there is no intervention

Timeline

• Start date: 2014-11-01
• Primary completion: 2016-09-01
• Completion: 2017-01-01
• First posted: 2015-03-19
• Last updated: 2019-05-09

Locations

13 sites across 1 country: France