Trials / Completed
CompletedNCT02391532
Effect of Probiotic Bacteria on Oral Candida in Frail Elderly
Effect of Probiotic Bacteria (L. Reuteri) on Oral Candida Counts in Frail Elderly
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 215 (actual)
- Sponsor
- University of Copenhagen · Academic / Other
- Sex
- All
- Age
- 60 Years
- Healthy volunteers
- Accepted
Summary
The aim of this study is to investigate the effect of daily intake of the probiotic Lactobacillus Reuteri on the prevalence and counts of oral Candida in frail elderly living in nursery homes.
Detailed description
The aim of the present study was to investigate the effect of a twice daily intake of lozenges containing probiotic Lactobacillus reuteri on the prevalence and counts of oral Candida in senior residents living in nursery homes. The material consists of 215 elderly persons (range 60 to 102 years) living in 20 different nursery homes in the County of Kronoberg, situated in the southern parts of Sweden. The subjects were consecutively enrolled after informed consent consisting of verbal and written information directed to the individual as well as to their relatives. The study employed a double-blind randomized placebo-controlled design.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | L. reuteri DSM 17938/ATCC PTA | Ingestion of active lozenge twice daily for 12 weeks |
| DIETARY_SUPPLEMENT | Placebo | Ingestion of placebo lozenge twice daily for 12 weeks |
Timeline
- Start date
- 2013-09-01
- Primary completion
- 2014-03-01
- Completion
- 2015-06-01
- First posted
- 2015-03-18
- Last updated
- 2015-08-11
Source: ClinicalTrials.gov record NCT02391532. Inclusion in this directory is not an endorsement.