NCT02391207

Hepatic Vein-sparing Hepatectomy for Colorectal Liver Metastases at the Caval Confluence

Hepatic Vein-sparing Hepatectomy for Colorectal Liver Metastases at the Caval Confluence: Validation on Intention-to-treat Analysis of a IOUS-guided Approach

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: University of Milan · Academic / Other
• Sex: All
• Age: 28 Years – 79 Years
• Healthy volunteers: Not accepted

Summary

Major hepatectomies are generally selected for tumors involving the hepatic vein (HV) at the caval confluence (CC). As alternative, HV reconstruction has been proposed. The present study aimed to evaluate the feasibility and safety of a HV-sparing policy guided by intraoperative ultrasonography (IOUS) in a cohort of patients having at least one colorectal liver metastasis (CLM) in contact with a HV at CC. HV section can be avoided in the large majority of cases thanking to CLMs detachment or to HV partial resection or reconstruction: this policy seems feasible, safe, reduces the need of major hepatectomies, and oncologically provides an adequate local control.

Conditions

• Secondary Malignant Neoplasm of Liver

Interventions

Type	Name	Description
PROCEDURE	Hepatic vein-sparing hepatectomy	HV detachment, partial resection and section on the basis of HV-CLM relationship

Timeline

• Start date: 2009-01-01
• Primary completion: 2012-12-01
• Completion: 2014-12-01
• First posted: 2015-03-18
• Last updated: 2015-03-18

Locations

1 site across 1 country: Italy