Trials / Completed
CompletedNCT02389868
Effects of Lovastatin on Human Platelet Proteome
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 15 (estimated)
- Sponsor
- Université de Sherbrooke · Academic / Other
- Sex
- All
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to evaluate the effects induced by the cholesterol-reducing drug Lovastatin on the platelet proteome of healthy volunteers. Our results may allow to recognize the cell signalling modifications induced by Lovastatin. Furthermore, the current study aims to characterize the biological and inter-individual variation of platelet's proteome as measured by liquid chromatography-tandem mass spectrometry. Lastly, the exploration of changes induced by Lovastatin on the platelet's proteome may allow the discovery of modifications relative to the effects of statins on hemostasis and the lipid profile.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Lovastatin |
Timeline
- Start date
- 2015-02-01
- Primary completion
- 2015-06-01
- Completion
- 2015-06-01
- First posted
- 2015-03-17
- Last updated
- 2015-06-16
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT02389868. Inclusion in this directory is not an endorsement.