NCT02389400

Methotrexate and Cytosine in Adult Langerhans Cell Histiocytosis

Efficacy and Tolerance of Combination Chemotherapy With Methotrexate and Cytosine Arabinoside in Newly Diagnosed Adult With Langerhans Cell Histiocytosis

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: Peking Union Medical College Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Study Type: Interventional Study Design: Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment purpose: This single arm clinical trial is studying efficacy and tolerance of combination chemotherapy with methotrexate and cytosine arabinoside in newly diagnosed adult with Langerhans cell histiocytosis.

Detailed description

This single arm clinical trial is studying efficacy and tolerance of combination chemotherapy with methotrexate and cytosine arabinoside in newly diagnosed adult with Langerhans cell histiocytosis.

Conditions

• Langerhans Cell Histiocytosis

Interventions

Type	Name	Description
DRUG	methotrexate	Single Group Assignment

Timeline

• Start date: 2014-01-01
• Primary completion: 2017-09-01
• Completion: 2017-09-01
• First posted: 2015-03-17
• Last updated: 2018-09-12

Locations

1 site across 1 country: China