NCT02388555

Perspective Analysis of Coronal Imbalance in Degenerative Scoliosis

Coronal Imbalance in Degenerative Lumbar Scoliosis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 284 (actual)
• Sponsor: Nanjing University School of Medicine · Academic / Other
• Sex: All
• Age: 50 Years – 82 Years
• Healthy volunteers: Not accepted

Summary

Currently there is paucity of information on the prevalence of pre-operative coronal imbalance in patients with degenerative lumbar scoliosis (DLS) and its influence on surgical outcomes. This study aims to investigate in DLS, the prevalence of coronal imbalance, to propose a novel classification system and to investigate whether pre-operative coronal imbalance affects clinical outcomes following osteotomy. A total of 284 DLS patients were recruited.

Detailed description

A total of 284 DLS patients were recruited into this two-stage study, among which 69 patients were treated by posterior-only correction and the remaining 215 patients received conservative treatment. Using pre-operative long-cassette X-ray films, all patients were classified based on coronal balance distance (CBD) defined as the horizontal distance between C7 plumb line and central sacral vertical line: Type A, CBD \< 3cm; Type B, CBD \> 3cm and C7PL shifts to the concave side of curve; Type C, CBD \> 3cm and C7PL shifts to the convex side of curve. The prevalence of pre-operative coronal imbalance was calculated for stage I study. Post-operative CBD in patients who received surgery was measured to evaluate clinical outcomes for stage II study.

Conditions

• Scoliosis

Interventions

Type	Name	Description
PROCEDURE	Posterior osteotomy correction	The DLS patients underwent osteotomy including pedicle subtraction osteotomy (PSO) or Smith-Petersen osteotomy (SPO)

Timeline

• Start date: 2010-01-01
• Primary completion: 2014-11-01
• Completion: 2015-01-01
• First posted: 2015-03-17
• Last updated: 2015-04-08