Trials / Unknown
UnknownNCT02385136
Temozolomide and Concomitant Whole Brain Radiotherapy in NSCLC Patients With Brain Metastases
Temozolomide and Concomitant Whole Brain Radiotherapy in NSCLC Patients With Brain Metastases: A Randomized Trial
- Status
- Unknown
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 135 (estimated)
- Sponsor
- Zhejiang Cancer Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to evaluate the safety profile and efficacy of whole brain radiotherapy (WBRT) concomitantly with temozolomide (TMZ) in patients with brain metastases (BM).Patients with BM were randomly assigned to 30 Gy of WBRT with or without concomitant TMZ (75 mg/m2/d) plus two cycles of TMZ (200 mg/m2/d for 5 days).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Temozolomide |
Timeline
- Start date
- 2015-04-01
- Primary completion
- 2016-12-01
- Completion
- 2018-12-01
- First posted
- 2015-03-11
- Last updated
- 2015-03-11
Source: ClinicalTrials.gov record NCT02385136. Inclusion in this directory is not an endorsement.