NCT02384707

Master Allergen Child Nutrition. Reintroduction of Small Doses

Reintroduction of Small Doses of Food in Allergic Children to Lightening the Elimination Diet.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 400 (estimated)
• Sponsor: University Hospital, Angers · Other Government
• Sex: All
• Age: 9 Months – 16 Years
• Healthy volunteers: Not accepted

Summary

Reintroduction of small doses of food in allergic children to lightening the elimination diet.

Detailed description

In four groups of allergic children (peanuts, wheat , milk and egg), a reintroduction of 4 small increasing doses of allergen is carried out progressively double-blind placebo- cons , randomized, during a hospitalization. The procedure for reintroduction of small doses (MPD) is stopped at the appearance of intolerance (in taking a dose of allergen or placebo) defined by the onset of allergic symptoms or objective severe abdominal pain within 45 minutes of taking.

Conditions

• Food Allergies

Interventions

Type	Name	Description
OTHER	allegic food	Reintroduction procedure for small doses : * Administration of the first dose * Clinical monitoring for 45 minutes * Administration of the second dose
OTHER	Placebo

Timeline

• Start date: 2011-05-01
• Primary completion: 2011-06-01
• Completion: 2015-12-01
• First posted: 2015-03-10
• Last updated: 2015-03-10

Locations

1 site across 1 country: France