NCT02383537

Biological Changes in the Adipose Tissue Among Pregnant Women With Diabetes

Biological Changes in the Adipose Tissue (RNA Profile) Among Pregnant Women With Diabetes

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 150 (estimated)
• Sponsor: Hadassah Medical Organization · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The aim of the research is to study the effect of miRNA, fat tissue and insulin resistance on the pathophysiology of diabetes during pregnancy. During the study fat tissue, Umbilical cord blood, placenta tissue and subcutaneous fat will be taken from pregnant diabetic woman over going a C-section. Healthy pregnant women will serve as a control group.

Detailed description

The aim of the research is to study the effect of miRNA, fat tissue and insulin resistance on the pathophysiology of diabetes during pregnancy. During the study: 1. fat tissue, Umbilical cord blood, placenta tissue and subcutaneous fat will be taken from pregnant diabetic woman over going a C-section. 2. Bloods will be analyzed for insulin, c-peptide, glucose and fat profile 3. Placenta and fat tissue will be analyzed for miRNA and total RNA 4. Clinical and anthropometric measurements will be taken from the mother 5. Placenta status will be taken

Conditions

• Pregnancy
• Diabetes

Interventions

Type	Name	Description
OTHER	Diabetes	the trial is observational with no intervention

Timeline

• Start date: 2017-04-01
• Primary completion: 2019-02-01
• Completion: 2020-02-01
• First posted: 2015-03-09
• Last updated: 2016-09-02