NCT02383485

Nonalcoholic Fatty Liver Disease and Atherosclerotic Risk in Children

Exercise and Overweight Children's Cognition (Supplement)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 175 (actual)
• Sponsor: Augusta University · Academic / Other
• Sex: All
• Age: 8 Years – 11 Years
• Healthy volunteers: Accepted

Summary

Nonalcoholic fatty liver disease is a serious health condition in overweight children which can lead to heart disease. This project will examine the links between liver health and cardiovascular risk factors in overweight and obese children, and will test the effect of a long-term after-school exercise program. Provision of comprehensive evidence for the benefits of exercise on children's health may reduce barriers to vigorous physical activity programs during a childhood obesity epidemic.

Detailed description

This is an ancillary study adding cardiometabolic outcome measures to an ongoing NIH-funded randomized trial of exercise in overweight children ("SMART study," R01 HL087923, P.I. Davis, NCT02227095). This presents the opportunity to obtain detailed measures of liver and vascular health to provide information about the effects of exercise on these conditions.

Conditions

• Overweight and Obesity
• Non-alcoholic Fatty Liver Disease

Interventions

Type	Name	Description
BEHAVIORAL	Exercise	Heart rate monitors worn by each child at each session
BEHAVIORAL	After-school program	Supervised recreational program with token economy

Timeline

• Start date: 2008-05-01
• Primary completion: 2013-05-01
• Completion: 2014-04-01
• First posted: 2015-03-09
• Last updated: 2015-03-09

Locations

1 site across 1 country: United States