Clinical Trials Directory

Trials / Unknown

UnknownNCT02382198

Study of Glycopyrrolate for Moderate-to-severe Sialorrhea in Parkinson's Disease

A Randomized, Placebo-controlled, 2-arm Parallel-group Superiority Phase II Study of GLYCOpyrrolate for Moderate-to-severe Sialorrhea in PARkinson's Disease

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
28 (estimated)
Sponsor
Ottawa Hospital Research Institute · Academic / Other
Sex
All
Age
30 Years
Healthy volunteers
Not accepted

Summary

Sialorrhea is a frequently occurring problem with detrimental effect on quality of life in 25% of PD patients. Currently, there is no intervention approved for sialorrhea in Parkinsons and evidence is only available for a 30-day effect or less. We hypothesize that glycopyrrolate will have a lasting effect in the reduction of sialorrhea in PD patients.

Detailed description

To assses if Glycopyrrolate has a long lasting effect on sialorrhea for patients with Parkinsons.

Conditions

Interventions

TypeNameDescription
DRUGGlycopyrrolateDrug to reduce drooling in patients with Parkinson's Decease.
DRUGPlacebo

Timeline

Start date
2016-07-01
Primary completion
2018-10-01
Completion
2018-12-01
First posted
2015-03-06
Last updated
2018-04-17

Locations

2 sites across 1 country: Canada

Source: ClinicalTrials.gov record NCT02382198. Inclusion in this directory is not an endorsement.