NCT02381028

Topical Treatment With Fresh Human Milk Versus Emollient on Atopic Eczema Spots in Young Children

Topical Treatment With Fresh Human Milk Versus Emollient on Atopic Eczema Spots in Young Children: A Small, Randomized, Split Body, Controlled, Blinded Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: Oslo University Hospital · Academic / Other
• Sex: All
• Age: 6 Years
• Healthy volunteers: Not accepted

Summary

The aim of this small pilot study is to assess the potential effects and risks of applying fresh human milk locally on eczema spots in children with atopic eczema. This is a split body, controlled, randomized and physician blinded pilot study, of children with atopic eczema with two similar contralateral eczema spots having a mother breastfeeding the child or a sibling. Fresh expressed milk and emollient is to be applied on the intervention spot and emollient alone on the control area, three times a day for four weeks. Severity and area of the eczema spots is evaluated weekly, and samples from milk and the spots were analysed weekly with respect to bacterial colonisation.

Conditions

• Atopic Eczema

Interventions

Type	Name	Description
OTHER	Human milk and emollient: Apobase creme® (Actavis Norway AS)	Topical application of human milk followed by emollient
OTHER	Emollient: Apobase creme® (Actavis Norway AS)	Topical application of emollient

Timeline

• Start date: 2008-10-01
• Primary completion: 2010-11-01
• Completion: 2010-11-01
• First posted: 2015-03-06
• Last updated: 2015-03-06