NCT02379546

The Effect of Anaesthesia Depth on Oculo-cardiac Reflex

The Effect of Anaesthesia Depth on Oculo-cardiac Reflex in Strabismus Surgery

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 64 (actual)
• Sponsor: Tokat Gaziosmanpasa University · Academic / Other
• Sex: All
• Age: 3 Years – 16 Years
• Healthy volunteers: Not accepted

Summary

This study was designed to determine the effect of the depth of anesthesia on the oculocardiac reflex (OCR) during pediatric strabismus surgery.

Detailed description

The oculo-cardiac reflex (OCR) is a trigeminovagal reflex which is started by the stimulus on the extra-ocular muscle and may lead to serious bradycardia or arrhythmia in the patients during strabismus surgery. It is presumed that the depth of anesthesia is one of the influencing factor on the OCR. But the clinical trials which are evaluating the relationship between the anesthesia depth and OCR are scarce. The main objective of this study is to determine the impact of the depth of anaesthesia that is adjusted with the bispectral index (BIS) monitor on the incidence of OCR in pediatric patients undergoing strabismus surgery.

Conditions

• Strabismus
• Anesthesia, General

Interventions

Type	Name	Description
DRUG	Desflurane	Desflurane will be used to maintain the anesthesia and the dose of desflurane will be adjusted according to the Bispectral İndex Monitoring
DEVICE	Bispectral index monitoring	Bispectral index monitoring (BIS XP, A-2000, VERSİON 3.31, Aspect Medical Systems, Newton, Mass, USA)will be used to determine the depth of anesthesia

Timeline

• Start date: 2013-08-01
• Primary completion: 2015-05-01
• Completion: 2015-05-01
• First posted: 2015-03-05
• Last updated: 2015-05-28

Locations

1 site across 1 country: Turkey (Türkiye)