NCT02376738

Regional Activation of Leukocytes in Coronary Artery Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 97 (actual)
• Sponsor: Sint Franciscus Gasthuis · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the role of leukocyte activation in coronary artery disease

Detailed description

1. The primary aim of REAL CAD is to determine regional differences of leukocyte activation in different vascular beds in vivo. 2. The secondary aim is to investigate differences in leukocyte activation between diabetic and CAD subjects and patients suffering from both. 3. The third aim is to investigate the relationship between complement components, triglycerides and leukocyte activation markers in order to gain more insight into the causative processes leading to activation of leukocytes. 4. The fourth aim is to get more insight in the MBL genotypes and serum levels of CAD and/or diabetic patients and the 'healthy' groups included in our study.

Conditions

• Inflammation
• Coronary Artery Disease

Timeline

• Start date: 2007-07-01
• Primary completion: 2008-09-01
• Completion: 2008-09-01
• First posted: 2015-03-03
• Last updated: 2015-03-03

Locations

2 sites across 1 country: Netherlands