NCT02372526

The Effect of Different Macronutrients on Gastrointestinal Hormone Secretion After Gastric Bypass Operation

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 18 (actual)
• Sponsor: Kirstine Nyvold Bojsen-Moeller · Academic / Other
• Sex: All
• Age: 25 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine the type of macronutrient (carbohydrate, lipid or protein) that most potently stimulates the endogen secretion of different gut hormones (primary outcome = Glucagon-Like peptide-1) in gastric bypass operated patients. The study also includes a comparison of the secretion of gut hormones after oral intake of lipid with or without a pancreatic lipase inhibitor.

Conditions

• Bariatric Surgery (Gastric Bypass)
• Overweight

Interventions

Type	Name	Description
OTHER	Mealtest: High protein 200 kcal 200 ml liquid meal consumed during 10 minutes
OTHER	Mealtest: High fat 200 kcal 200 ml liquid meal consumed during 10 minutes
OTHER	Mealtest: High carbohydrate 200 kcal 200 ml liquid meal consumed during 10 minutes
OTHER	Mealtest: High fat 200 kcal 200 ml liquid meal with pancreatic lipase inhibitor consumed during 10 minutes

Timeline

• Start date: 2015-01-01
• Primary completion: 2016-08-01
• Completion: 2017-06-01
• First posted: 2015-02-26
• Last updated: 2017-02-07

Locations

1 site across 1 country: Denmark