NCT02368249

Does Terlipressin Improve Renal Outcome After Liver Surgery

Does Terlipressin Improve Renal Outcome After Liver Surgery - A Double-Blinded Randomized Control Trial (TIROL-Trial)

• Status: Withdrawn
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Zurich · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators aim to address whether terlipressin improves the renal outcome after liver surgery. Therefore the investigators are planning to conduct a double-blinded randomized control trial. The investigators will randomize patients undergoing any kind of liver surgery and being at increased moderate to high risk for post-operative acute renal failure into a control group receiving post- operative a placebo or into a group receiving post-operatively terlipressin in combination with human albumin.

Conditions

• Kidney Failure

Interventions

Type	Name	Description
DRUG	Terlipressin	Patients are receiving a post-operative intravenous terlipressin treatment in association with human albumin to preserve the renal function
DRUG	Placebo	Patients are receiving a post-operative intravenous Ringer's lactate solution

Timeline

• Start date: 2020-01-01
• Primary completion: 2025-02-01
• Completion: 2025-02-01
• First posted: 2015-02-23
• Last updated: 2017-05-05

Locations

1 site across 1 country: Switzerland