NCT02364349

A Comparative Study on Local Allergic Responses of Bee Venom and Essential Bee Venom Pharmacopuncture

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Jaseng Hospital of Korean Medicine · Academic / Other
• Sex: All
• Age: 20 Years – 39 Years
• Healthy volunteers: Accepted

Summary

This double-blinded randomized clinical trial investigates any differences in allergic responses elicited by Bee Venom (BV) and Essential Bee Venom (eBV).

Detailed description

This double-blinded randomized clinical trial investigates difference in allergic responses elicited by Bee Venom (BV) and Essential Bee Venom (eBV). Twenty healthy volunteers aged 20-40 years were randomly allocated to the 2 groups and administered eBV and BV on left and right forearm, respectively, in accordance with group allocation. Physician, participant, and outcome assessor were blinded to group allocation. Local pain, swelling, itching, redness, wheals and adverse reactions were recorded by timepoint before and after treatment.

Conditions

• Healthy Volunteers

Interventions

Type	Name	Description
DRUG	Bee Venom (BV)	Raw Bee Venom
DRUG	Essential Bee Venom (e-BV)	Bee venom without Hyaluronidase, Lysophospholipase, α-D-glucosidase, PLA2, Adolapin

Timeline

• Start date: 2015-01-01
• Primary completion: 2015-02-01
• Completion: 2015-02-01
• First posted: 2015-02-18
• Last updated: 2018-11-07

Locations

1 site across 1 country: South Korea