NCT02364180

Electromyography in Patients on Chronic Pyridostigmine Therapy

Electromyography With Repetitive Nerve Stimulation in Patients on Chronic Pyridostigmine Therapy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: University of Toledo Health Science Campus · Academic / Other
• Sex: All
• Age: 12 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

We intend to measure evoked EMG at two sites in subjects who are chronically taking pyridostigmine.

Detailed description

The investigators are intending to enroll Patients who are chronically treated with pyridostigmine for the treatment of any medical condition and presenting at the investigators' outpatient clinics for follow up appointment. Subjects taking pyridostigmine for the treatment of myasthenia gravis will be excluded. Both adults and children older than 12 years of age will be approached. Those subjects that agree to participate will be asked to sign an informed consent. For the participation of minors a parental (or guardian) consent and subject assent will be obtained. Those that participate will answer a few questions pertaining to their medical history and will then undergo electromyograph (CMAP) measurement with repetitive stimulation at 2 sites (ulnar nerve at the wrist and the accessory nerve in the neck). Evoked electromyogram will be recorded on a computer hard drive. Eight percent or greater decrement in the CMAP response on repetitive stimulation will be considered positive.

Conditions

• Muscle Weakness

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Electromyography (EMG)

Timeline

• Start date: 2013-12-01
• Primary completion: 2016-07-01
• Completion: 2016-07-01
• First posted: 2015-02-16
• Last updated: 2017-05-09
• Results posted: 2017-03-31

Locations

1 site across 1 country: United States