NCT02363166

Analysis of CA-MRSA Transmission: An ED Population Sampling Strategy

Molecular Epidemiology and Phylodynamic and Phylogeographic Analysis of Community-associated Methicillin-resistant Staphylococcus Aureus (CA-MRSA) Transmission: An Emergency Department Population Sampling Strategy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 575 (actual)
• Sponsor: University of Florida · Academic / Other
• Sex: All
• Age: 1 Month
• Healthy volunteers: Not accepted

Summary

Given that the Emergency Department (ED) has become the entry way for large populations of patients into the health care system, a strategy of sampling MRSA isolates in ED populations and merging this information with patient-level data may present a window to hypothesize and investigate CA-MRSA transmission within the community and its impact on hospital-acquired infections.

Detailed description

Prospective cross-sectional study involving 500 patients enrolled over a one year period at the UFHealth Shands Hospital's Adult and Pediatric Emergency Department. The collected information will serve as pilot data for a future large comprehensive multi-site study. Patients will have a wound culture and a nasal swab obtained as part of the study, which will be assessed for MRSA isolates using next-generation whole genome sequencing. The principal investigator or PI designee will also survey participants and review hospital records.

Conditions

• Methicillin-Resistant Staphylococcus Aureus

Interventions

Type	Name	Description
OTHER	Acute Abscess Group	Samples collected for culture and sensitivity testing depending on acute abscess, or skin/soft tissue infection.

Timeline

• Start date: 2015-08-01
• Primary completion: 2018-04-04
• Completion: 2018-04-04
• First posted: 2015-02-13
• Last updated: 2024-08-21

Locations

1 site across 1 country: United States