NCT02356900

Hyperbaric VO2max Study

Effects of High Intensity Interval Training in a Hyperoxic-hyperbaric Environment on Exercise Performance at Altitude

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

This study seeks to examine the effectiveness of training while in a hyperoxic-hyperbaric environment for exercise performance at altitude. Subjects will complete a short, high-intensity interval training (HIT) program inside the hyperbaric chamber.Before and after this training phase, all subjects will be tested for maximum aerobic capacity at a simulated high altitude of 15,000ft in a hypobaric chamber, as well as for molecular markers of mitochondrial oxidative capacity in a skeletal muscle biopsy. A group of individuals of similar characteristics completing this training program in a normoxic-normobaric environment will serve as a control.

Conditions

• Exercise Training

Interventions

Type	Name	Description
PROCEDURE	Hyperoxic hyperbaric interval exercise training	Six 30-min high-intensity interval training sessions completed 3-times a week while at 1.4 ATA of oxygen in a hyperbaric chamber.
PROCEDURE	Normoxic, normobaric, interval exercise training	Six 30-min high-intensity interval training sessions completed 3-times a week.
DRUG	Oxygen	Used in Hyperoxic hyperbaric interval exercise training intervention

Timeline

• Start date: 2015-02-01
• Primary completion: 2016-05-01
• Completion: 2016-05-01
• First posted: 2015-02-05
• Last updated: 2017-05-17
• Results posted: 2017-04-12

Locations

1 site across 1 country: United States