Trials / Completed
CompletedNCT02350725
Furosemide Pharmacodynamics and Pharmacokinetics After Subcutaneous or Oral Administration
A Single Center, Randomized, Open-label, Cross-over Exploratory Study to Evaluate the Pharmacodynamic and Pharmacokinetic Response to a Subcutaneous Administration or Oral Administration of Furosemide in Subjects With Heart Failure Presenting With Chronic Fluid Overload
- Status
- Completed
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 10 (actual)
- Sponsor
- scPharmaceuticals, Inc. · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this pilot study is to investigate the pharmacodynamic and pharmacokinetic parameters of a novel furosemide formulation administered subcutaneously as compared to oral furosemide.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Furosemide injection solution for subcutaneous administration (80 mg) | |
| DRUG | Oral Furosemide tablets (80 mg) |
Timeline
- Start date
- 2014-12-01
- Primary completion
- 2015-06-01
- Completion
- 2015-06-01
- First posted
- 2015-01-30
- Last updated
- 2018-06-27
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT02350725. Inclusion in this directory is not an endorsement.