Clinical Trials Directory

Trials / Completed

CompletedNCT02348944

Biological Variability in Cartilage Specific Biomarkers in Healthy Volunteers.

Evaluation of Biological Variability in Cartilage Specific Biomarkers (Coll2-1, Coll2-1NO2, FIB3-1 and FIB 3-2) in Healthy Volunteers.

Status
Completed
Phase
Study type
Observational
Enrollment
15 (actual)
Sponsor
Artialis · Industry
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

The purposes of the study are to assess intra individual biological variability of serum and urinary cartilage specific biomarkers and define the best standardized conditions for blood and urine sampling in the frame of biomarkers dosage.

Detailed description

To assess intra individual biological variability of serum and urinary cartilage specific biomarkers and define the best standardized conditions for blood and urine sampling in the frame of biomarkers dosage. Variation factors assessed are: * Fasting condition * Sampling time * Sampling season * Physical activity * Duration and temperature of total blood treatment * Type of blood collection tube.

Conditions

Interventions

TypeNameDescription
OTHERserum and urine sampleSerum and urine samples will be collected at baseline, weeks2, 16, 52 and 68 to assess intra-individual biological variability of cartilage-specific biomarkers Coll2-1/Coll2-1NO2 / FIB3-1 and FIB3-2.

Timeline

Start date
2013-08-01
Primary completion
2014-12-01
Completion
2014-12-01
First posted
2015-01-28
Last updated
2015-01-28

Locations

1 site across 1 country: Belgium

Source: ClinicalTrials.gov record NCT02348944. Inclusion in this directory is not an endorsement.