NCT02348242

Ocular Surface Disorders in Patients in Intensive Care Units, a Comparative Study of Three Preventive Approaches

Ocular Surface Disorders in Patients in Intensive Care Units, a Comparative Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 49 (actual)
• Sponsor: Fondation Ophtalmologique Adolphe de Rothschild · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

60% of the patients hospitalized in intensive care and sedated suffer from insufficient inferior eyelid occlusion. Thus, they are at risk for corneal damage (estimated risk 20% to 57%). The prevention of such corneal damage can be done using several techniques (artificial tears, eyelid occlusion dressing, aqueous gel). The efficacy of these techniques has never been compared in a rigorous study. Therefore it is not yet possible to determine an evidence-based strategy to prevent corneal damage in intensive care patients. This study aims at assessing the efficacy of primary prevention of corneal lesions in intensive care patients, in order to elaborate an evidence-based nursing protocol.

Conditions

• Corneal Diseases

Interventions

Type	Name	Description
DEVICE	Aqueous Gel	1 drop of Dexpanthenol® 0.2% aqueous gel in the eye every 6 hours
DEVICE	Eyelid Occlusion Dressing	Eyelid occlusion using pro-ophta® eyelid occlusion dressing, dressing to be verified every 6 hours and replaced daily
DEVICE	Artificial Tears	1 drop of Phylarm® artificial tears in the eye every 6 hours

Timeline

• Start date: 2014-12-01
• Primary completion: 2016-02-01
• Completion: 2016-02-01
• First posted: 2015-01-28
• Last updated: 2017-02-13

Locations

1 site across 1 country: France