Trials / Unknown
UnknownNCT02344641
Efficacy and Mechanism of Exenatide on Improving Heart Function in Type 2 Diabetes With Heart Failure Patients
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 234 (estimated)
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
The study evaluates the efficacy of heart function improvements in type 2 diabetes and heart failure patients with exenatide, and also investigates the mechanisms of exenatide improving heart function.
Detailed description
The study enrolls 234 patients with type 2 diabetes and heart failure. The patients have an New York Heart Association (NYHA) functional class of II to IV, are randomly assigned to 2 groups. One group use exenatide , the other group is control group and each group has 117 patients. At the baseline, the 3rd day, the 28th day patients are required to complete the heart failure examination: plasma N-terminal pro-B-type natriuretic peptide(NT-proBNP), 6-min walking distance, echocardiographic measures, patient quality of life(MLHFQ). At the end of 4-week follow-up, we evaluate the efficacy of heart function improvements after treatment with exenatide and also investigate the mechanisms of exenatide improving heart function .
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Exenatide |
Timeline
- Start date
- 2015-01-01
- Primary completion
- 2016-12-01
- Completion
- 2016-12-01
- First posted
- 2015-01-26
- Last updated
- 2015-01-27
Source: ClinicalTrials.gov record NCT02344641. Inclusion in this directory is not an endorsement.