Trials / Completed
CompletedNCT02336659
Influence of Gut Hormones on Food Intake After Roux-en-Y Gastric Bypass Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- Hvidovre University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is to examine the effect of GLP-1 and other gut-secreted hormones (glucagon, GIP, grelin and PYY) on food-intake, appetite and glucose metabolism after Roux-en-Y gastric bypass surgery.
Detailed description
To do this the effect of combined GLP-1 receptor blockade by Exendin 9-39 and DPP-4-inhibition will be evaluated.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | exendin 9-39 | Exendin 9-39 is a specific GLP-1 receptor antagonist |
| DRUG | sitagliptin | DPP-4 Inhibition |
| OTHER | Placebo | Saline |
Timeline
- Start date
- 2014-04-01
- Primary completion
- 2016-05-01
- Completion
- 2016-06-01
- First posted
- 2015-01-13
- Last updated
- 2016-06-21
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT02336659. Inclusion in this directory is not an endorsement.