Trials / Completed
CompletedNCT02331108
A Comparison of Inhalation vs. Intravenous Induction
A Comparison of the Effect on Temperature Between Patients Induced With Intravenous Propofol vs Inhalation Induction With Sevoflurane
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 331 (actual)
- Sponsor
- Albert Einstein Healthcare Network · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
To compart differences on the effect on core temperature between anesthetic induction with intravenous propofol versus inhalation induction with sevoflurane
Detailed description
Hypothermia occurs with anesthetic induction due to redistribution hypothermia. Hypothermia has adverse effects and should be avoided or minimized. Intravenous propofol induction is the most common technique used for anesthetic induction. There is preliminary evidence that there is less redistribution hypothermia when anesthetic induction is achieved by inhalation induction compared to intravenous induction. There is not enough data to compel a change in practice patterns. This study will enroll a larger number of patients in order to provide stronger evidence that there is a significant difference between induction techniques on body temperature. Patients will be randomly assigned to two variation of inhalation induction techniques and two variations of intravenous induction. The effect on temperature between the four groups will be compared. Reducing the degree of hypothermia has the potential to decrease surgical infection rate as well as providing other benefits to patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Selection of anesthetic induction technique | Standard anesthesia care will be provided after induction based on randomization. Temperatures will be monitored every 15 minutes |
Timeline
- Start date
- 2014-08-01
- Primary completion
- 2015-10-01
- Completion
- 2016-04-01
- First posted
- 2015-01-06
- Last updated
- 2017-04-17
- Results posted
- 2017-04-17
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02331108. Inclusion in this directory is not an endorsement.