NCT02329977

Rate of Duodenal-biliary Reflux Increases in Patients With Recurrent Common Bile Duct Stones

Rate of Duodenal-biliary Reflux Increases in Patients With Recurrent Common Bile Duct Stones: Direct Evidence From Barium Meal Examination

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 64 (actual)
• Sponsor: Air Force Military Medical University, China · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

ERCP is the primary choice for removal of common bile duct stone (CBDS) currently. However, 4-24% patients underwent recurrence after successful clearance of CBDS. Stone re-formation due to chronic inflammation of biliary duct is generally considered an important cause of CBDS recurrence, which is associated with duodenal-biliary reflux (DBR) after sphincterotomy. Although it was believed that DBR was the important cause of CBDS recurrence, the direct evidence was still lacking. Here we conducted a case control study to investigate the DBR rate in patients with recurrent CBDS after ERCP.

Conditions

• Common Bile Duct Gall Stones
• Common Bile Duct GallStones

Interventions

Type	Name	Description
OTHER	standard barium meal examination	All eligible patients received standard barium meal examination, MRCP and enhanced abdominal CT.

Timeline

• Start date: 2013-06-01
• Primary completion: 2013-12-01
• Completion: 2014-01-01
• First posted: 2015-01-01
• Last updated: 2015-12-02

Locations

1 site across 1 country: China