NCT02328339

Tea and Forearm Blood Flow

Forearm Blood Flow Response to Acute Consumption of Black Tea

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Unilever R&D · Industry
• Sex: All
• Age: 45 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The study will explore the benefit of tea for microcirculation. Subjects will consume tea ar a placebo matched for taste and appearance in a blinded cross over design.

Detailed description

Epidemiological studies indicate that regular consumption of black tea reduces the risk of cardiovascular diseases. Tea consumption can result in improvements in endothelial function of conduit arteries as measured by flow mediated dilation. Less is known however about its effects in other vascular beds. The study will test the hypothesis that tea affects endothelial function in the muscle microcirculation. This will be done by assessment of forearm blood flow using venous occlusion plethysmography after consumption of black tea against or placebo in a randomised, full cross-over study in 20 healthy middle-aged to elderly subjects

Conditions

• Vascular Function

Interventions

Type	Name	Description
OTHER	Tea	Black tea infusion equivalent to approximately 530 mg total polyphenols expressed as gallic acid equivalents
OTHER	Placebo	Placebo matched to tea with respect to taste and appearance

Timeline

• Start date: 2015-01-01
• Primary completion: 2015-08-01
• Completion: 2015-08-01
• First posted: 2014-12-31
• Last updated: 2015-08-31