NCT02325765

Study of the Corelation Between Circulating Nuclearsome and SIRS Happened After Congential Cardiac Surgery

Corelation Between Circulating Nuclearsome and SIRS Happened After Congential Cardiac Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Shanghai Children's Medical Center · Academic / Other
• Sex: All
• Age: 1 Month – 3 Years
• Healthy volunteers: Not accepted

Summary

In this study，the investigators want to determine the corelation between circulating nuclearsome and the development of SIRS occured after congenital cardiac surgery, including the serverity of organ damage and inflamation.

Detailed description

Blood was collected from study participants at 6 time points; 1) post-anesthesia induction, 2) post-op hour 0, 3) post-op hour 4, 4) post-op hour 24, 5) post-op hour 48, and 6) post-op hour 72. At each of the 6 time points blood was analyzed for levels of the following:histone,blood routine test , c-reaction protein, procalcitonin, N-terminal pro-brain natriuretic,the hepatorenal function，cardiac function and pulmonary function

Conditions

• Congential Cardiac Surgery

Timeline

• Start date: 2014-04-01
• Primary completion: 2015-11-01
• Completion: 2015-11-01
• First posted: 2014-12-25
• Last updated: 2015-12-02

Locations

1 site across 1 country: China