NCT02324855

Long-term Airway Clearance Therapy in Non-cystic Fibrosis Bronchiectasis

Long Term Airway Clearance Therapy in Non Cystic Fibrosis Bronchiectasis: a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 26 (actual)
• Sponsor: Universidad San Jorge · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main aim is to analyze whether the routine use of chest physiotherapy in non cystic fibrosis bronchiectasis (NCFB) improves the cough severity and the quality of life in this population. In addition, the secondary end-points include incidences of exacerbations, changes in lung function, exercise capacity, airways inflammation, sputum analysis and eventual adverse events.

Detailed description

The present project will be a single-blind , randomized, controlled trial of 12-month daily performing chest physiotherapy compared with usual care, followed by a 3-month intervention-free in non-cystic fibrosis bronchiectasis. Intervention group will perform daily autonomous airway clearance techniques (positive expiratory pressure technique through Acapella device and autogenic drainage technique). Patients will receive professional sessions once a month. Control group will receive their usual care and educational sessions about their disease. Physiotherapist will call them once a month. During the study period the patients' pharmacological treatment remained unchanged

Conditions

• Bronchiectasis

Interventions

Type	Name	Description
OTHER	Chest physiotherapy plus usual care	Subjects will perform daily chest physiotherapy during at least 30 minutes. Patients will perform a slow expiratory airway clearance technique combined with positive expiratory pressure device (Acapella device, Murray et al.) Each patient will receive 12 supervised professional sessions (once a month).

Timeline

• Start date: 2015-10-01
• Primary completion: 2020-06-01
• Completion: 2020-06-01
• First posted: 2014-12-24
• Last updated: 2021-05-18

Locations

1 site across 1 country: Spain