NCT02324478

Exploration of Autonomic Nervous System by Photoplethysmography

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 52 (estimated)
• Sponsor: ASST Fatebenefratelli Sacco · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The autonomic nervous system state (ANSS) and the autonomic nervous system state index (ANSSi) - two indices derived from the pulse photo-plethysmography analysis - have been recently advocated as a measure of sympathetic activity in the anesthetized patients, but their validity has not been yet demonstrated. We will conduct a study aiming to assess if ANSS and ANSSi reflect autonomic nervous system modulation on cardiovascular system in healthy humans under general anaesthesia.

Conditions

• Intervention Affecting Autonomic Nervous System

Interventions

Type	Name	Description
PROCEDURE	autonomic nervous system analysis	electrocardiographic and pulse-photoplethysmographic waves of patients under general anesthesia for laparoscopic cholecystectomy will be recorded on a laptop pc for offline analysis of autonomic nervous system modulation a three main time point: 1) at baseline, before general anesthesia induction, 2) five min after tracheal tube placement, 3) five min after pneumoperitoneum insufflation.

Timeline

• Start date: 2015-03-01
• Primary completion: 2015-06-01
• Completion: 2015-06-01
• First posted: 2014-12-24
• Last updated: 2015-06-25

Locations

1 site across 1 country: Italy