NCT02323672

Salivary and Serum Levels of Chemerin and MMP-9 in Oral Premalignant and Malignant Lesions

Salivary and Serum Levels of Chemerin and MMP-9 in Oral Precancer and Oral Squamous Cell Carcinoma.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 45 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 40 Years – 50 Years
• Healthy volunteers: Accepted

Summary

45 individuals were subdivided into 3 groups, 15 patients with oral premalignant lesions, 15 patients with oral malignant lesions and 15 control individuals. Levels of chemerin and MMP-9 were evaluated in serum and saliva of these subjects utilizing the ELISA technique.

Detailed description

45 individuals were subdivided into 3 groups, 15 patients suffering from oral premalignant lesions, 15 patients suffering from oral malignant lesions and 15 individuals having age, gender and periodontal status matched with both patients groups acting as a control group. Serum and whole unstimulated saliva samples were collected from all the included groups in order to determine chemerin and MMP-9 in serum and saliva utilizing the ELISA technique.

Conditions

• Precancerous Conditions
• Oral Cancer

Timeline

• Start date: 2014-02-01
• Primary completion: 2014-09-01
• Completion: 2014-10-01
• First posted: 2014-12-23
• Last updated: 2017-02-10