NCT02323347

Cut-Off Progesterone Values Deleterious for In Vitro Fertilization and Fresh Embryo Transfer

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,901 (actual)
• Sponsor: Fundacion Dexeus · Academic / Other
• Sex: Female
• Age: 18 Years – 49 Years
• Healthy volunteers: Not accepted

Summary

At which deleterious cut off value of progesterone on day of HCG (P-hCG) in our IVF program should fresh embryo transfer (ET) be cancelled?

Detailed description

There is still an ongoing debate on the effect of subtle increased P-hCG concentration on pregnancy outcome after fresh ET. No consensus on the cut-off value to define increased P-hCG seems to exist. It is accepted that high P advances endometrium, leading to asynchrony between the implanting embryo and the endometrium, and resulting in implantation failure. A freeze all embryos policy and postponement of ET in subsequent frozen-thawed cycle has been proposed.

Conditions

• Progesterone
• Fertilization in Vitro
• Infertility
• Pregnancy

Interventions

Type	Name	Description
OTHER	Progesterone	Progesterone level

Timeline

• Start date: 2009-01-01
• Primary completion: 2014-03-01
• Completion: 2014-03-01
• First posted: 2014-12-23
• Last updated: 2014-12-23