NCT02323256

Neurophysiological Measures of Auditory Perception and Rehabilitation in Cochlear Implanted Patients

Neurophysiological Measures During Sound and Speech Perception in Cochlear Implanted Patients and Development of New Speech Rehabilitation Tools

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 91 (actual)
• Sponsor: Hospices Civils de Lyon · Academic / Other
• Sex: All
• Age: 1 Year – 70 Years
• Healthy volunteers: Accepted

Summary

This study aims at investigating new automatic fitting techniques for cochlear implant patients based on objective measures. For this reason, the evolution of these neurophysiological measures, expressing the encoding of pure tones and speech, will be characterized in cochlear implanted patients as a function of post-implantation time and will be compared to those of normal hearing subjects. Moreover, the effect of auditory training with new tools based on serious games will be assessed.

Conditions

• Deafness

Interventions

Type	Name	Description
OTHER	Auditory steady-state response ASSR	comparison of ASSR amplitudes in response to amplitude-modulated sounds delivered at different intensities
OTHER	Speech-ABR
OTHER	Acoustic Change Complex ACC	comparison of ACC complex in response to changes within speech stimulation
OTHER	P1-N1-P2 complex and Mismatch Negativity MMN	comparison of amplitudes and latencies of P1-N1-P2 complex and MMN generated in response to the detection of changes in a series of auditory stimulation

Timeline

• Start date: 2014-07-01
• Primary completion: 2018-05-01
• Completion: 2018-05-01
• First posted: 2014-12-23
• Last updated: 2025-08-11

Locations

1 site across 1 country: France