Clinical Trials Directory

Trials / Completed

CompletedNCT02319408

Immune Boost In Non-Small Cell Lung Cancer

A Randomized Phase II Study of Radiation Induced Immune Boost in Operable Non-small Cell Lung Cancer

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
36 (actual)
Sponsor
University Hospital Heidelberg · Academic / Other
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

Insufficient migration and activation of tumour specific effector T cells seems to be the one important reason for inadequate host anti-tumour immune response. Ionizing radiation can induce a variety of immune responses. The goal of this randomized trial is to assess if a preoperative single fraction low dose radiation is able to improve anti-tumour immune response in operable early stage lung cancer.

Conditions

Interventions

TypeNameDescription
RADIATIONPreoperative radiationLobectomy for lung cancer following preoperative radiation

Timeline

Start date
2016-04-01
Primary completion
2020-02-01
Completion
2020-02-01
First posted
2014-12-18
Last updated
2022-05-23

Locations

2 sites across 1 country: Germany

Source: ClinicalTrials.gov record NCT02319408. Inclusion in this directory is not an endorsement.