NCT02317224

The Safety and Efficacy of "3-Hole" Subxiphorid Approach in the Treatment of Anterior Mediastinal Tumor

Comparison of Safety and Efficacy Among "3-Hole" Subxiphorid Approach, Trans Sternal Approach and VATS in Surgical Treatment of Anterior Mediastinal Tumor

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 240 (estimated)
• Sponsor: Tang-Du Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Surgery plays an important role in the treatment of anterior mediastinum disease. The major surgical approaches include: cervical approach, mid-sternal approach, cervical combined mid-sternal approach and video-assisted thoracoscopic approach. The cervical approach is rarely adopted because of its restricted visual field. The cervical combined mid-sternal approach have a broader field of vision, given this advantage, the surgeon can remove the thymus and its surrounding fat tissue more thoroughly. But the trauma of this approach is much larger, and the postoperative complication is also a serious problem. The video-assisted thoracoscope is often adopted by left or right approach, this minimally invasive procedure can not remove anterior mediastinum fat thoroughly. In clinical practice, the investigators designed a new method named "3-Hole" subxiphoid approach. This study is designed to compare the safety and validity between this new method and others.

Conditions

• Thymectomy
• Myasthenia Gravis

Interventions

Type	Name	Description
PROCEDURE	"3-Hole" subxiphorid and subcostal approach	"3-Hole" subxiphorid and subcostal approach anterior mediastinum tumor resection
PROCEDURE	Trans sternal approach	Trans sternal approach anterior mediastinum tumor resection
PROCEDURE	VATS approach	Video-assisted thoracoscope anterior mediastinum tumor resection

Timeline

• Start date: 2014-08-01
• Primary completion: 2024-12-01
• Completion: 2024-12-01
• First posted: 2014-12-15
• Last updated: 2014-12-15

Locations

1 site across 1 country: China